AFP and neoplasm: In the adjusted Cox multivariate survival analysis, there were 5 independent predictors associated with adverse outcome: serum albumin < 4 g/dL (HR 1.621, 95% CI 1.175–2.236, p = 0.003), AFP level ≥ 400 ng/mL (HR 2.223, 95% CI 1.591–3.107, p<0.001), tumor size > 10 cm (HR 1.501, 95% CI 1.081–2.083, p = 0.015), presence of PVTT (HR 1.919, 95% CI 1.385–2.658, p<0.001) and TACE (HR 2.922, 95% CI 2.090–4.086, p<0.001).