The combined VEGFA (rs699947 CC/CA) and VEGFR2 (rs2305948 TT) genotype both presented protective effects on developing CHD (CCCT vs CCCC: OR = 0.51, 95% CI = 0.28–0.95, P < 0.05; CATT vs CCCC: OR = 0.38, 95% CI = 0.22–0.67, P < 0.001) (Table 8). Here, VEGFA is linked to coronary artery disorder.