USP8 and pituitary gland adenoma: Pituitary adenomas have been associated with mutations in numerous other genes, including succinate dehydrogenase (SDH) [31], ubiquitin-specific peptidase 8 (USP8) [32, 33], cyclin-dependent kinase inhibitor 1B (CDKN1B) [34], aryl hydrocarbon receptor interacting protein (AIP) [35], and cAMP-dependent protein kinase type 1-alpha regulatory subunit (PRKAR1A) [36].