As shown in Figure 3a-3e, using MTS assay (Figure 3a), in vitro cell growth assay (Figure 3b), and colony formation assays (Figure 3c), we found that VentX exerts strong inhibition on the growth of these cancer cells lacking a functional p53 (P<0.01, respectively) (Figure 3d and 3e). The gene discussed is TP53; the disease is cancer.