AKT2 and breast cancer: Overexpression of AKT2 was sufficient to reverse miR-124-inhibited cell proliferation, migration and invasion in both MCF7 (Figure 6C, 6E and 6G) and MDA-MB-231 cells (Figure 6D, 6F and 6H), suggesting that the inhibitory effect of miR-124 in human BC cells is via the function of its target AKT2.