WIPI1 and diabetes mellitus: The inhibition of EHMT2 has been reported to activate autophagy genes, leading to the transcriptional activation of microtubule-associated protein 1 light chain 3 (MAP1LC3/LC3), WD repeat domain phosphoinositide-interacting protein 1 (WIPI1), and the diabetes- and obesity-regulated gene (DOR) in a c-Jun-dependent manner [29], as well as the expression of B-cell lymphoma 19-kDa interacting protein (BNIP) [30].