Moreover, oxidative stress markers (TBARS, GSH) and nitrosative stress markers (iNOS, 3-tyrosine nitrated proteins) were similar in NOX2−/−/HFD mice and in WT/SCD as well as in NOX2−/−/SCD mice (Fig. 2 and Supplementary Fig. S2). This evidence concerns the gene NOS2 and Schnyder corneal dystrophy.