We found that GAS6 triggered mTOR signaling in prostate cancer, with increases seen in both mTORC1 and mTORC2 (Figures 4D and S6A–S6B), and these were diminished by the mTORC1 inhibitor rapamycin and the dual mTORC1/2 inhibitor pp242 (Figures 4E, S6C–S6D, and S7A–S7B). Here, GAS6 is linked to Familial prostate cancer.