AJUBA and neoplasm: Consistent with these findings, our study showed that AJUBA mainly localized in the cytoplasm in tumor tissues, and the percentage of nucleus staining dramatically decreased in tumor tissues compared with non-tumor tissues, suggesting that AJUBA may transfer from nucleus to cytoplasm and different domains of AJUBA and the subcellular location of AJUBA affect the subcellular activities of AJUBA and, thus, tumor cell functions.