CDK4 and cancer: We selected the representative target genes of OncomiRs for an additional Western blot analysis, including the tumor suppressors PTEN, p27kip1, metallopeptidase inhibitor 3 (TIMP3) and reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) that are directly targeted by i-lncRNA, and the oncogenic factors p38/mitogen-activated protein kinases (MAPK), Survivin, cyclin-dependent kinase 4 (CDK4) and c-myc that are indirectly related with the changes of cancer cell malignant behaviors mediated by i-lncRNA expression.