To obtain further insight concerning involvement of MALAT1 in molecular pathogenesis of breast cancer, we used quantitative real-time reverse-transcriptase–polymerase chain reaction (qRT–PCR) assay, to quantify the full-length (FL) and an alternatively spliced variant (Δsv) of MALAT1 mRNA expression in a series of 446 patients with unilateral invasive breast tumours and known long-term outcome. This evidence concerns the gene MALAT1 and breast carcinoma.