Recurrent mutations in the promoter region of TERT gene, namely the c.-146:C > T and the c.-124:C > T mutations, were recently reported in several tumors, including melanomas, bladder, hepatocarcinoma, thyroid carcinomas, and gliomas (Huang et al. 2013; Vinagre et al. 2013; Killela et al. 2013; Horn et al. 2013; Bell et al. 2015; Batista et al. 2016). This evidence concerns the gene TERT and glioma.