SRPK1 and viral infectious disease: Some viral-infection-related genes, such as Il1a (Pruitt et al. 1995; Dinarello 2011) and Srpk1 (Sciabica et al. 2003; Wang et al. 2014), exhibited gains of stop codons (Figure 4), which may correlate with the ability of the AHR to serve as a pathogen carrier.