The co-expression profiles for ACSL4 were applied to annotate gene ontology using GeneGo Metacore with a strong cluster of 3,444 genes across a panel of 53 breast carcinoma and 6 normal breast samples, 117 genes across a panel of 10 brain tumor and 5 normal brain samples, 509 genes across a panel of 20 colorectal cancer and 20 normal colorectal samples, and 54 genes across a panel of 25 lung adenocarcinoma and 25 normal lung samples. The gene discussed is ACSL4; the disease is brain neoplasm.