In LN there was a statistically significant increase in TGF-β (Mann-Whitney U test; P = 0.018) and IL-10 (Mann-Whitney U test; P = 0.003) when compared to NID; whereas previously, at 6 months, there had been only mRNA expression for IFN-γ. The gene discussed is TGFB1; the disease is lobular neoplasia.