IL6 and AIDS: We developed a biomarker score (the “IL-6 & D-dimer score”), which optimally combines markers of inflammation and coagulation to predict the risk of serious non-AIDS conditions or death from any cause (SNA/death) among HIV-infected adults on suppressive ART, and a biomarker model to estimate the effect of sustained long-term reductions in IL-6 and D-dimer levels on the risk of SNA/death.