Potential benefits of earlier LAM diagnosis include the possibility to inform women about the risk of a pneumothorax, pregnancy, the use of contraceptives, and lifestyle choices, such as scuba diving or smoking, as well as the opportunity to start mTOR inhibitor therapy, even if this choice is currently limited to patients with lung function declining rapidly or respiratory symptoms, chylous pleural effusion or ascites [43]. The gene discussed is MTOR; the disease is pneumothorax.