Although the differentially expressed genes were associated with a wide range of effector functions, proinflammatory cytokines and chemokines were heavily featured, with HD monocytes having significantly increased expression of IL6, IL12B, IL19, IL23A, CCL8, CCL19, CCL20, CXCL6 and CSF2 gene transcripts. The gene discussed is IL19; the disease is Huntington disease.