Although the differentially expressed genes were associated with a wide range of effector functions, proinflammatory cytokines and chemokines were heavily featured, with HD monocytes having significantly increased expression of IL6, IL12B, IL19, IL23A, CCL8, CCL19, CCL20, CXCL6 and CSF2 gene transcripts. This evidence concerns the gene CCL20 and Huntington disease.