Interestingly, more and more studies indicated RACK1 is interacted with some proteins (such as, ZEBRA, LMP1 and A73) encoded by Epstein–Barr virus (EBV) which has been implicated in the molecular abnormalities leading to NPC [19–22], implying that RACK1 probably impacts N NPC development and progression. This evidence concerns the gene RACK1 and nasopharyngeal carcinoma.