Mutations in the NEB gene are associated with autosomal recessive Nemaline myopathy 2 (OMIM 2560), a congenital form of which may present with US findings during pregnancy, similar to those reported in this fetus (OMIM, 2016; Lammens et al., 1997; Ryan et al., 2001). This evidence concerns the gene NEB and nemaline myopathy 2.