NDUFA13 and neoplasm: In complementary in vivo xenograft mice models studies, ectopic GRIM-19 expression significantly inhibited tumor formation in SGC-7901 and BGC-823 cells (Figure 3F and 3G) whereas knockdown of GRIM-19 significantly promoted tumor growth in SGC-7901 cells, as shown in the xenograft tumor growth curve (Figure 3H).