SNP microarray data, available on 349 matched tumor and normal samples [30], were analyzed for tumor CIN profiles and germline variants in 15 genes previously associated with telomere length in the population-based studies (ACYP2, BCL2L1, CTC1, CXCR4, MEN1, MRE11A, NAF1, OBFC1, RECQL5, RTEL1, TERC, TERT, TNKS, ZNF208 and ZNF676) (Supplementary Table S1). This evidence concerns the gene RTEL1 and neoplasm.