To test whether the expression of TAZ is also associated with EGFR signaling in vivo, the expression of the p-EGFR, p-AKT and p-ERK1/2 proteins was examined in the xenograft tumor tissues formed by TAZ-knockdown and TAZ-overexpressing U87 cells (Figure 5E and 5F). The gene discussed is MAPK3; the disease is neoplasm.