Moreover, loss of CCND1 expression also contributed to inhibition of NSCLC cell (both A549 and SPC-A-1 cells) growth (62% or 51% of decrease in A549 or SPC-A-1 cells) (Figure 4B–4E) and metastasis (58% or 55% of decrease in migration, 66% or 63% of decrease in invasion in A549 or SPC-A-1 cells) (Figure 4F–4I). Here, CCND1 is linked to non-small cell lung carcinoma.