Then, we compared lincRNA-p21 expression in 37 glioma tissues, including 9 low grade astrocytomas (LGA, Grade II), 16 anaplastic astrocytomas (AA, Grade III) and 12 glioblastoma multiforme (GBM, Grade IV), with 8 normal brain tissues. This evidence concerns the gene CDKN1A and anaplastic astrocytoma.