The selective induction of the above-mentioned proinflammatory cytokines during infection with 107 CFU of the cda1Δ2Δ3Δ mutant was associated with minimal changes in the concentrations of cytokines driving a Th2 response, such as IL-4, IL-5, IL-10, and IL-13 (Fig. 2C). This evidence concerns the gene IL4 and infection.