In contrast, even though we observed statistically significant differences in the induction levels of IL-4 and IL-10 in mice infected with 107 CFU of the cda1Δ2Δ3Δ mutant and mice infected with 107 CFU of the wild type, the magnitudes of upregulation for infection with 107 CFU of the cda1Δ2Δ3Δ mutant were small (5- to 10-fold) compared to the levels seen for the Th1-specific inflammatory molecules mentioned above (Fig. 2B and C). Here, IL10 is linked to infection.