This latter result could be due to the wide involvement of this chemokine in diabetes-associated vascular bed alterations [37, 64], where CXCL10, among other Th1-type biomediators, is described to be increased (devaraj et al. 2009 cytokine) and responsible for triggering vascular alteration and damage [14, 64]. Here, CXCL10 is linked to diabetes mellitus.