CXCL10 and diabetic cardiomyopathy: Concerning in vivo data, we show that in diabetic cardiomyopathy serum CXCL10 positive or negative variation after sildenafil intake categorized subjects as drug responders vs. non-responders; in fact, as revealed by ROC analysis, CXCL10 serum level equal or higher than cut-off value (930 pg/ml) is significantly predictive of response to sildenafil.