CXCL10 level was significantly different in r and nr subgroups (P < 0.01, Fig. 5c);in particular, r subgroup showed CXCL10 serum level similar to subjects affected by diabetes without sings of cardiac disease (DM), but significantly different from subjects with non-diabetic cardiomyopathy (IC, P < 0.05 vs. DM and r; Fig. 5c). The gene discussed is CXCL10; the disease is heart disorder.