Since β2a, β3a, β3c, and β3e subunits have all been shown to induce partial or total inactivation of KCa1.1 [36, 39, 45–47], the lack of inactivation shows that these subunits are not involved in the KCa1.1 channel in RA-FLS. The gene discussed is KCNMA1; the disease is rheumatoid arthritis.