Similarly, difference in rate of Cryptosporidium infection by diarrhea status was statistically significant in patients with a CD4 level < 200 cells/μl (no diarrhea 15 %, acute diarrhea 6 %, chronic diarrhea 28.3 %; χ2 = 9.12, df = 2, P = 0.01). This evidence concerns the gene CD4 and cryptosporidiosis.