Interestingly, Ataxin-10 (Atxn10) and Huntingtin-associated protein 1 (Hap1), proteins associated with the neurodegenerative disease spinocerebellar ataxia 10 (SCA10) and Huntington’s disease, respectively, were identified as UBQLN2 interactors. This evidence concerns the gene HAP1 and neurodegenerative disease.