Recent large-scale genome-wide association studies identified FGF14 as locus of single-nucleotide polymorphisms and as such a potential disease-associated gene for schizophrenia, bipolar disease, depression, epilepsy and addictive behaviors,17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27 corroborating initial reports of missense mutations in FGF14 as genetic links to the neurodegenerative disorder, spinocerebellar ataxia 27.28, 29 These results highlight the possibility of an as yet undiscovered and pivotal role for the FGF14 gene in psychiatric disorders. The gene discussed is FGF14; the disease is depressive disorder.