Of interest, two geneswithin the ‘ubiquitin-mediated proteolysis' annotated module(TMEM106B and SCAMP1) and one within the‘circadian clock' annotated module (DCTN1) overlap witha previous study that had used CFG-based approach to validate bloodbiomarkers for delusions, a core symptom of psychoticdisorders.20 An additionalgene (RAB18) within the ‘ubiquitin-mediatedproteolysis' module was also validated as a SCZ biomarker using theCFG approach.18 This evidence concerns the gene SCAMP1 and Delusion.