Its downregulation correlates with poor prognosis in lung adenocarinoma and cell cycle.8 It also sensitizes ovarian cancer cells to cisplantin.10 Its overexpression attenuates lung cancer cell invasiveness through inhibiting PTTG1.9 MiR-186 therefore may be a candidate that link gastric adenocarcinoma to less aggressive phenotype. This evidence concerns the gene PTTG1 and ovarian cancer.