CPEB4 and hepatocellular carcinoma: To determine whether CPEB4-KD promotes in vivo proliferation of HCC cells, we used HepG2 cells, which express a medium-to-high level of CPEB4 [27], transfected with the plasmid expressing the GFP reporter and CPEB4-KD sequence, which is identical to the validated one used in the previous study [27].