TWIST1 and craniosynostosis: Within the framework of a broader study into the genetic causes of craniosynostosis, WGS was applied to DNA of 18 Dutch index cases with coronal synostosis and negative testing for FGFR2, FGFR3, and TWIST1, and their family members (43 samples in total), by Complete Genomics, a BGI company (Mountain View, CA), as described in Drmanac et al.