To begin to address why IL-15 figures more prominently than IL-7 in T-cell reprogramming in lymphopenia though both of them are of similar functional effects [21], we first assessed changes in expression of IL-7Rα and IL-15Rβ on naïve T-cells or Te cells following in vitro stimulation with IL-7 or IL-15. Here, IL2RB is linked to lymphopenia.