CREBBP and juvenile myelomonocytic leukemia: We analyzed leukemic granulocyte DNA from 64 children with JMML (17 of which overlapped with the 44-patient series used for epigenetic analysis) for CREBBP exon sequence variants using the Agilent SureSelect v4.0 capture technique and deep-sequencing, resulting in an average CREBBP exon depth of 82 reads.