CD34 and chronic myelogenous leukemia, BCR-ABL1 positive: To better understand alterations in Hh signaling in primary human CML stem and progenitor cell populations, we sorted primary CP-CML or normal CD34+ cells into pure haemopoietic stem cell (HSC/LSC; lin−CD34+CD38−CD90+), common myeloid progenitor (CMP; lin−CD34+CD38+CD123+CD45RA−), granulocyte-macrophage progenitor (GMP; lin−CD34+CD38+CD123+CD45RA+) and megakaryocyte-erythroid progenitor (MEP; lin−CD34+CD38+CD123−CD45RA−) subpopulations by FACS.