The genetic predisposition to TB associated with Vitamin D receptor (VDR) gene polymorphisms was considered a prime candidate for TB susceptibility but results from a meta-analysis have proved inconclusive [17] although a link between VDR polymorphisms and response to therapy in terms of time to fast sputum conversion rate with anti TB treatment in FF; Taql Tt and non-FF; TT genotypes respectively for pulmonary TB has been suggested [24]. The gene discussed is VDR; the disease is tuberculosis.