And, in view of the limitations of animal model, it is necessary to be cautious when it is extended to human patients with autism; secondly, LXR agonist T0901317 can activated both LXRα and LXRβ, while, the main purpose of our study was to investigate the relationship between LXRβ and ASD, so the roles of LXRα and LXRβ activated by LXR agonist on ASD need to be further explored; thirdly, we cannot observe the specific changes of the indicators before and after treatment in the same mice because we selected the brain tissue of mice for our experiment. Here, NR1H2 is linked to autism.