Previous studies have identified different risk factors for increasing the incidence of DM like age, body mass index (BMI), systolic blood pressure (BP), fasting plasma glucose, glycated hemoglobin (HbA1c), etc. Clinically, DM expresses hyperglycemia, dyslipidemia, hyperhomocysteinemia, and decreased β-cell or insulin function and section to induce insulin resistance [10]. The gene discussed is INS; the disease is diabetes mellitus.