We initially examined CUL2 and HPV16 E7 mRNA expressions using qRT-PCR in a panel of 137 cervical specimens, including 36 HPV negative and 37 HPV16 positive normal cervical tissues, 33 HPV16 positive CIN 2-3, and 31 HPV16 positive invasive cervical cancer tissues. Here, CUL2 is linked to cervical carcinoma.