VLDLR and infection: To examine whether these repeats participate in HCV entry, LDLR and VLDLR mutants with these repeats deleted were expressed in SR/LD-DKO Huh7 cells and the intracellular HCV RNA levels were determined upon infection with HCVcc at an MOI of 1 by qRT-PCR at 24 h post-infection (Fig 6B).