There were two pilot studies conducted of GLP-1 analogs for AD (3-year 230-patient randomized trial using exenatide sponsored by National Institute on Aging (Clinical Trials identifier: NCT01255163) and a 12-month, 200-patient trial of liraglutide conducted by the Imperial College London (Clinical Trials identifier: NCT01843075)). Here, GLP1R is linked to Alzheimer disease.