CEP290 was present at the base of cilia in control iPSCs, but not in LCA iPSCs in which aberrant splicing of the cryptic exon 26-X-27 was detected (Figures S3A and S3B). Cilia incidence was significantly reduced in LCA iPSCs compared to control iPSCs, although the length of the remaining cilia was similar (Figures S3C–S3E). The gene discussed is CEP290; the disease is Leber congenital amaurosis.