ATP5PO and Alzheimer disease: In sharp contrast, the expression levels of a, b and c, as well as α and β subunits remained unaltered in either synaptic or nonsynaptic mitochondria from 5xFAD mice at any tested age (Supplementary Fig. 3a–d), indicating that OSCP expression is selectively suppressed in parallel with the manifestation of AD-like symptoms in 5xFAD mice.