Primary fibroblasts obtained from 3 ALS patients harboring the same mutation (p.A382T) in TARDBP gene, 4 patients with pathological expansion of the hexanucleotide repeat sequence in C9ORF72 gene and 4 healthy controls (Additional file 1: Table S1) were transfected with the mitochondria-tagging plasmid pDsRed2Mito or live-labeled with the Mitotracker Red dye. Here, TARDBP is linked to amyotrophic lateral sclerosis.