To do this, we created gene signatures for each of our three previously identified Trp53-null transplant classes using a two-class (class x versus all others) Significance Analysis of Microarrays (SAM) analysis across a 385-sample microarray dataset consisting of 27 murine models of mammary carcinoma, and normal mammary tissue (Pfefferle et al., 2013). The gene discussed is TP53; the disease is breast carcinoma.