The D-Score varied across the three Trp53-null subtypes, with the p53null-ClaudinlowEx subtype being the lowest, the p53null-BasalEx being intermediate, and the p53null-LuminalEx being the highest (P<0.05) (Fig. 1B); even though the p53null-LuminalEx subtype had the highest D-Score among the three p53-null subtypes, its score was still relatively intermediate when compared across the entire diverse murine tumor dataset. Here, TP53 is linked to neoplasm.