Since we demonstrated that IFNAR1-mediated signaling increased the abundance of endogenous Enterobacteriaceae during influenza infection, we aimed to test whether they could similarly affect the growth of Salmonella Typhimurium (S. Typhimurium), a leading cause of acute gastroenteritis and inflammatory diarrhea, using a mouse model of acute colitis. Here, IFNAR1 is linked to inflammatory diarrhea.