LTBP2 and primary congenital glaucoma: A number of chromosomal loci associated with primary congenital glaucoma (PCG) have been identified in humans (OMIM 231300, 600975, 613085, and 613086) and mutations in the cytochrome P450 gene, CYP1B1, and LTBP2 gene at two of these loci were identified in families segregating PCG [6, 7].